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Side effects of GLP-1 diabetes and weight reduction drugs: “Ozempic face” and more

GLP-1 drugs have been shown to be very effective for diabetes and weight reduction, but in addition they have uncomfortable side effects. One of those uncomfortable side effects is “ozympic face,” where the skin on the face becomes wrinkled and wrinkled. The “Ozympic Face” was coined as a reference to one in all these drugs, although any rapid weight reduction may cause it.

What are GLP-1 drugs and the way do they work?

GLP-1 drugs, also called GLP-1 agonists, are short names for glucagon-like peptide-1 receptor agonists. GLP-1 receptor agonists mimic the GLP-1 hormone that is of course released within the stomach in response to food.

When you eat, your digestive system breaks down carbohydrates into easy sugars that travel through your bloodstream. GLP-1 stimulates the discharge of insulin out of your pancreas. Insulin helps move glucose (sugar) out of the bloodstream and into your cells, where it may possibly be used for nutrition and energy.

In individuals with type 2 diabetes, the body's cells are proof against the results of insulin, the body doesn't make enough insulin, or each. GLP-1 agonists stimulate the pancreas to release insulin and suppress the discharge of one other hormone called glucagon, each of which help control blood sugar levels in individuals with type 2 diabetes.

These drugs also work to suppress appetite within the brain and delay emptying, so you're feeling fuller for longer. These effects can result in weight reduction, which will be a crucial a part of diabetes management. GLP-1 agonists have been used to treat type 2 diabetes for nearly 20 years.

More recently, the FDA has approved several GLP-1 agonists for weight reduction in obese individuals who shouldn't have diabetes. When used for chubby or obesity, drugs are often prescribed in higher doses than those prescribed for diabetes.

What GLP-1 drugs can be found?

Ten GLP-1 drugs are FDA-approved for the treatment of either type 2 diabetes or weight reduction. Some GLP-1 agonists have the identical generic name but are marketed under different brand names and approved for various purposes, depending on the dose and the way they're taken.

GLP-1 drugs

common name

Brand name

Approved use

Semaglutide injection

Ozempic

Type 2 diabetes

Semaglutide injection

Vagus

Weight loss

Semaglutide tablets

Rybellus

Type 2 diabetes

Liraglutide

Victoza

Type 2 diabetes

Liraglutide

Saxenda

Weight loss

Tirzepatide

Monjaro

Type 2 diabetes

Tirzepatide

Zip sure

Weight loss

Dolaglutide

The truth

Type 2 diabetes

Exenatide

Byta

Type 2 diabetes

Exenatide prolonged release

Bydureon

Type 2 diabetes

Differences between GLP-1 drugs include:

  • Foods GLP-1 drugs for weight reduction normally involve higher doses than the identical drug used to administer diabetes.
  • How are they taken? Most are given by injection, but there's a pill option (Rybelsus).
  • Additional advantages. Some have been found to guard the center, and should profit people liable to heart attack.
  • age All will be utilized by adults, but some are also approved for kids.
  • Tolerance. If your body can't tolerate one GLP-1 drug, you may try one other drug.

“Ozympic face” as a side effect of GLP-1 drugs

You can have heard of “Ozempic face” as a side effect of GLP-1 drugs, although this term is misleading since it is a side effect of any GLP-1 drug or one other reason for rapid weight reduction. May be.

Rapid lack of fat on the face will be attributable to:

  • A hole look on the face
  • Changes in the dimensions of the lips, cheeks and chin
  • Wrinkles on the face
  • Sunken eyes
  • Jaws drooping across the jaw and neck.

If the load loss is more gradual, these changes is probably not as noticeable. It is the rapid rate of weight reduction that happens with GLP-1 drugs that will further explain the facial changes.

If the uncomfortable side effects of “Ozempic face” are significant, they will be treated with cosmetic surgery.

Other uncomfortable side effects of GLP-1 drugs

Gastrointestinal symptoms—nausea, vomiting, diarrhea, and constipation—are by far probably the most common uncomfortable side effects of GLP-1 drugs.

  • Nausea will be controlled by avoiding strong smells and eating crackers, mint, or ginger-based foods or beverages about half an hour after taking GLP-1 medication.
  • Vomiting will be managed by staying well hydrated and eating smaller, more frequent meals.
  • Diarrhea will be controlled by drinking loads of water and avoiding dairy products and high-fiber foods until symptoms subside.
  • Constipation will be controlled by getting enough fiber in your weight-reduction plan and drinking loads of water.

To help avoid gastrointestinal uncomfortable side effects of GLP-1 medications:

  • Eat slowly and stop when full.
  • Keep small portions.
  • Avoid being too lively immediately after eating.

Less common but more serious uncomfortable side effects of GLP-1 agonists include:

  • Pancreatitis, inflammation of the pancreas that causes abdominal pain.
  • gastroparesis, during which the movement of food through the stomach is slowed or stopped.
  • Intestinal obstruction, a blockage that forestalls food from passing through the intestines.
  • Gallstone attack and bile duct obstruction.

When to See a Doctor About GLP-1 Drug Side Effects

Most uncomfortable side effects of GLP-1 drugs usually are not serious. You should seek immediate medical attention if you've got:

  • Severe vomiting and diarrhea
  • Severe pain or tenderness in your abdomen
  • Inability to pass gas or move bowels.
  • Jaundice (yellowing of the skin).

Also, tell your doctor that you simply take GLP-1 medications in the event you are having surgery or a procedure that involves general anesthesia. Because GLP-1 drugs slow digestion, it is best to stop taking them just a few days before receiving anesthesia to ensure your stomach is empty.