For the past three a long time, HIV treatment and prevention have made amazing progress.
Now this can be a manageable infection. A one that takes HIV medicine with HIV, before his immune system decreases, before he can expect a live live Unless someone without HIV.
The same medicines Stop the transmission Viruses to sexual partners.
Is still There is no effective HIV vaccine. But there are extremely effective medicines to stop HIV infection without HIV, which is at greater risk of acquiring it.
These medicines are often called “Previous Exhibition Profilexes” or Trap. They come as a pill, which requires either day by day, or “”Demand on“Before and after sexual sex. An injection It has been shielded from HIV for six months recently has been approved In the United States.
So with such an efficient HIV treatment and preparation, why are we still? To spend millions Looking for HIV treatment?
Not everyone has access to those medicines
Access to HIV Drugs and PEP will depend on the supply of health clinics, health professionals, and sources of drug supply and distribution. In some countries, this infrastructure will not be protected.
For example, earlier this yr, dissolved by US President Donald Trump USAID Foreign Aid Program Many low -income countries are susceptible to supplying HIV drugs.
This shows the present approach to treatment and prevention. HIV needs a protected, uninterrupted supply of drugs, and without it, lives can be lost and its number New matters of HIV Will stand up.
Another example is a six -month preparation injection that remains to be approved within the United States. This drug has an excellent potential to manage HIV whether it is made available and low-cost in most HIV -burdened countries.
But low -income countries that access this expensive drug seem uncertain, even when it could possibly be made in a component of its current cost, As some researchers say.
Therefore, despite the success of HIV drugs and Prep, the uncertainty system of health care and high drug costs implies that we cannot depend on them to eliminate the continuing global HIV outbreak. That is why we still must see other options.
Are people not already 'well'?
Around the world, At least Seven people HIV has been “treated”-or has a minimum of a long-term everlasting amnesty. This implies that after HIV stops drugs, they’ve not had any HIVs who’ve made any duplication of their blood for months or years.
In every case, a HIV person also had a deadly cancer that requires a bone marrow transplant. Each of them was just like the donor, which had a selected genetic variation, which resulted in the shortage of HIV receptors in the important thing bone cells.
After the bone marrow transplant, the recipients stopped HIV drugs, without the identity level of the virus return. The recent immune cells made within the transplant bone marrow had a shortage of HIV receptors. This prevented the virus from affecting and copying cells.
But this genetic variation Is very rare. There can be a bone marrow transplantation Related to dangerous and extreme resources. So while this strategy has worked for some people, it shouldn’t be an prolonged possibility to treat HIV more extensively.
So we’d like to proceed to search for other options for every other option, including basic laboratory research to deliver us there.
What have I heard about 'progress'?
HIV treatment prevents HIV imitation, which causes immune damage. But there are places within the body where the virus “hides” and can’t reach the drugs. If the drug is stopped, the “Ivakit” comes out of HIV hiding and replicated again. Therefore, it could possibly damage the immune system, which causes HIV -related disease.
One point is to attempt to force the invisible or HIV to open space, so the drugs can goal it. This is a method called “shock and hit”. And recently an example of Australian research within the media as “Advance“Looking for HIV treatment.
Researchers in Melbourne have developed a lipid nano particle – a small ball of fat – which surrounds Messenger RNA (or MRNA) and provides “message” to the affected white blood cells. It indicates cells Disclosure “Hiding” HIV.
The theory, will allow the immune system or HIV drug to focus on the virus.
This discovery is a very important step. However, it remains to be within the laboratory phase of the test, and is barely one piece of the puzzle.
We can say the identical Many other results Herald as moving Near the treatment of HIV.
Human clinical trials need more research on safety and utility before testing. Such trials start with a small number and take a few years to the trial process. These and other measures toward treatment are slow and expensive, but are essential.
The vital thing is that any treatment will eventually have to be very low in order that it’s value it and low-cost. Globally low -income countries.
So where does it leave us?
A HIV Treatment It is cheaper and expanded could have a profound impact on human health globally, Especially for people living with HIV. There is a protracted and difficult path to attain, which involves resolving quite a few scientific puzzles, followed by implementing challenges.
In the meantime, HIV -risk people to make sure access to check and prevention intervention – akin to Prep and Safe Injection Equipment – may be very vital. People with HIV also need everlasting access to effective treatment – no matter where they live.